The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases
نویسندگان
چکیده
منابع مشابه
Metalloproteinase-Dependent TLR2 Ectodomain Shedding is Involved in Soluble Toll-Like Receptor 2 (sTLR2) Production
Toll-like receptor (TLR) 2, a type I membrane receptor that plays a key role in innate immunity, recognizes conserved molecules in pathogens, and triggering an inflammatory response. It has been associated with inflammatory and autoimmune diseases. Soluble TLR2 (sTLR2) variants have been identified in human body fluids, and the TLR2 ectodomain can negatively regulate TLR2 activation by behaving...
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1Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA 2Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA 3Department of Molecular Microbiology and Immunology, University of Southern California School of Medicine, Los Angeles, CA 90033, USA 4Malari Program, Seattle Biomedical Research Institute, Seattle, WA 98109, US...
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ژورنال
عنوان ژورنال: BMC Immunology
سال: 2014
ISSN: 1471-2172
DOI: 10.1186/s12865-014-0055-y